Interest in the public health significance of trace levels of pharmaceuticals in potable water is increasing, particularly with regard to the effects of long-term, low-dose exposures. To assess health risks and establish target concentrations for water treatment, human health risk-based screening levels for 15 pharmaceutically active ingredients and four metabolites were compared to concentrations detected at 19 drinking water treatment plants across the United States. Compounds were selected based on rate of use, likelihood of occurrence, and potential for toxicity. Screening levels were established based on animal toxicity data and adverse effects at therapeutic doses, focusing largely on reproductive and developmental toxicity and carcinogenicity. Calculated drinking water equivalent levels (DWELs) ranged from 0.49 μg/L (risperidone) to 20,000 μg/L (naproxen). None of the 10 detected compounds exceeded their DWEL.

Ratios of DWELs to maximum detected concentrations ranged from 110 (phenytoin) to 6,000,000 (sulfamethoxazole). Based on this evaluation, adverse health effects from targeted pharmaceuticals occurring in U.S. Drinking water are not expected. Learn more about these metrics Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals.

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Within United Kingdom About this Item: Pitman Publishing, 1990. Condition: Used; Good. Dispatched, from the UK, within 48 hours of ordering. This book is in good condition but will show signs of previous ownership. El Mas Loco Libro Pdf Immortals. Please expect some creasing to the spine and/or minor damage to the cover. Damaged book.

Please note this is a damaged book. The condition of this book is as stated above, however this book is slightly damaged in some way. Typically a grazed corner or torn cover. Seller Inventory # CHL2458932 1. Within United Kingdom About this Item: Pitman Publishing, 1990. Condition: Used; Acceptable.

Autodesk 3ds Max 2013 English_win_32bit Crack. Dispatched, from the UK, within 48 hours of ordering. The book is perfectly readable and fit for use, although it shows signs of previous ownership. The spine is likely creased and the cover scuffed or slightly torn. Textbooks will typically have an amount of underlining and/or highlighting, as well as notes. If this book is over 5 years old, then please expect the pages to be yellowing or to have age spots.

Damaged book. Please note this is a damaged book. The condition of this book is as stated above, however this book is slightly damaged in some way.

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This book is dirty and has significant shelf wear, however all text is there and readable, as such it is acceptable for sale, and is still a good read. Seller Inventory # CHL2488376 2. Within United Kingdom About this Item: Pitman Publishing, 1990. Condition: Used; Good. Dispatched, from the UK, within 48 hours of ordering. This book is in good condition but will show signs of previous ownership. Please expect some creasing to the spine and/or minor damage to the cover.